O 2 -substituted...

Organic compounds -- part of the class 532-570 series – Organic compounds – Diazooxide or diazotate

Reexamination Certificate

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C514S149000

Reexamination Certificate

active

07081524

ABSTRACT:
The present invention provides O2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates (1-[(2-carboxylato)pyrrolidin-1-yl]diazeniumdiolates) of the formulain which R and R22are as described herein. Also provided is a composition comprising such a compound and a carrier. The 1-[(2-carboxylato)pyrrolidin-1-yl]diazeniumdiolates compounds release nitric oxide under physiological conditions and are useful for treating biological disorders.

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