Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing


Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0


548103, 424 9, C07F 722




m-Radiohalo-aniline is a stable intermediate for preparing biotin-m-radiohalo-anilide to be used as an imaging agent or therapeutic agent. The invention also contemplates m-aminophenyltrialkylstannane which can be radiohalogenated and linked to biotin.

Eaborn et al., J Chem Soc. (B), 1967, p. 1036.
Visser et al., J Labelled Compounds and Radiopharmaceuticals XVII(5), p. 657 (1980).
Narula et al., "Method of Radiohalogenation of Protein . . . ", J. Nucl. Med. 28, 725 (#715) 1987.
Srivastava et al., "Design and Synthesis of a New N-(p-[.sup.125 I]Iodophenyl)-Maleimide ([.sup.125 I]) PM)", J. Nucl. Med 28, 726 (#717( 1987.
Srivastava et al, "N-(p-Iodophenyl)Maleimide . . . )", J. Nucl. Med. 27, 1047 (#697) 1986.
Hnatowich et al., J. of Nuclear Med., vol. 28, pp. 1294-1302 (1987).
Livaniou et al., J. of Nuclear Med., vol. 28, pp. 1430-1434 (1987).
Wursthorn et al., J. of Organometallic Chemistry, vol. 140, pp. 29-39 (1977).
D. S. Wilbur et al., J. Nuclear Medicine, vol. 27, 959 (No. 335) (1986).
D. S. Wilbur et al., Poster from Sixth International Symposium on Radiopharmaceutical Chemistry, Boston, Jun. 1986.
S. Wilbur et al., Poster and Abstract from Second International Conf. on Monoclonal Antibody Immunoconjugates for Cancer, Mar. 1987.
M. Hylarides et al., J. Nuclear Medicine, vol. 28, 560 (No. 14) (1987).
S. W. Hadley et al., J. Nuclear Medicine, vol. 28, 725 (No. 7612).
Zalutsky et al., Appl. Radiat. Isotopes, vol. 38, No. 12, 1051-1055 (1987).
An Improved Method for the Radiohalogenation of Monoclonal Antibodies, Zalutsky et al., from: Immunological Approaches to the Diagnosis and Therapy of Breast Cancer, edited by Roberto L. Ceriani (Plenum Publishing Corp., 1987).
European Patent Application Publication EP 0203764 A2--Wilbur et al., (published Dec. 3, 1986).


Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.


M-aminophenyltrialkylstannane does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with M-aminophenyltrialkylstannane, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and M-aminophenyltrialkylstannane will most certainly appreciate the feedback.

Rate now


Profile ID: LFUS-PAI-O-391347

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.