Lipases and lipase extracts, their preparation process and their

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

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424 946, 435134, C12N 920, A61K 3754

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active

050752316

ABSTRACT:
Process for the preparation of a gastric lipase. The stomachs of rabbits or horses undergo extraction by an acid aqueous medium, the lipase extract is salted out by the addition of hydrosoluble salts then, by filtration on a molecular sieve, followed by separation using ion exchange chromatography, an elution fraction containing the lipase is collected.
Medicament for fighting against malabsorptions of fatty substances.

REFERENCES:
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Hamosh, M. et al., (1979), J. Biol. Chem. 254(23), 12121-12125.
Hamosh, M. et al., (1981), J. Clin. Invest. 67, 838-846.
Tiruppathi, C. et al., (1982), Biochim. Biophys. Acta 712, 692-697.
Fink, C. S. et al., (1985), Am. J. Physiol. 248, 68-72.

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