Jak kinases and regulation of cytokine signal transduction

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S320100, C435S455000, C435S325000

Reexamination Certificate

active

06969760

ABSTRACT:
The invention relates generally to the Jak family of kinases. This includes the DNA and amino acid sequences for Jak 3 kinases. Additionally, the invention concerns expression vectors comprising DNA sequences encoding a Jak 3 kinase and host cell containing such expression vectors.

REFERENCES:
patent: 5190931 (1993-03-01), Inouye
patent: 5658791 (1997-08-01), Wilkes et al.
patent: 5705625 (1998-01-01), Civin et al.
patent: 5914393 (1999-06-01), Coleman et al.
patent: 6136595 (2000-10-01), Ihle et al.
patent: 6210654 (2001-04-01), Ihle et al.
patent: WO 92/10519 (1992-06-01), None
patent: WO 93/15201 (1993-08-01), None
Fuortes, M. Accession No. U08340. Apr. 21, 1994.
Kennell, D.E. Principles and Practices of Nucleic acid hybridization. Progr. Nucl. Acid Res. Mol. Biol. 11:259-301, 1971.
Littman et al. Nature 326:85-88, 1987.
Firmbach-Kraft et. al., tyk2, prototype of a novel class of non-receptor tyrosine kinase genes; 1990, Oncogene 5: 1329-1336.
Takahashi et. al.; Molecular cloning of rat JAK3, a novel member of the JAK family of protein tyrosine kinases; 1994, FEBS Letters 342:124-128.
Kawamura et. al.; Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes; 1994, Proc. Natl. Acad. Sci. vol. 91: 6374-6378.
Harper et. al.; JAK2, a third member of the JAK family of protein tyrosine kinases, 1992, Oncogene 7: 1347-1353.
Wilks et. al., Two Novel Protein-Tyrosine Kinases, Each with a Second Phosphotransferase-Related Catalytic Domain, Define a New Class of Protein Kinase, 1991; Molecular and Cellular Biology: 2057-2065.
Rane et. al.; JAK3; A novel JAK kinase associated with terminal differentiation of hematopoietic cells, 1994, Oncogene 9: 2415-2423.
Ngo et.al.; Computational Complexity, Protein Structure Prediction, and the Levinthal Paradox; 1994, The Protein Folding Problem and Tertiary Structure Prediction: 491-495.
Rudinger, Characteristics of the amino acids as components of a peptide hormone sequence, 1976; Peptide Hormones:1-7.
Argotsinger, L.S. et al., “Identification of JAK2 as a Growth Hormone Receptor-Associated Tyrosine Kinase,”Cell 74:237-244, Cell Press (Jul. 1993).
Bartholomew, C. and J.N. Ihle, “Retroviral Insertions 90-Kilebases Proximal to the Evi-1 Mycloid Transforming Gene Activate Transcription from the Normal Promoter,”Mol. Cell. Biol. 11(4): 1820-1828, American Society for Microbiology (1991).
Bird, T.A. et al., “Evidence that NAP (Nitrogen-Activated Protein) Kinase Activation May Be a Necessary but not Sufficient Signal for a Restricted Subset of Responses in IL-1 Treated Epidermoid Cells,”Cytokine 4(6):429-440, International Cytokine Society, Academic Press Ltd, (Nov. 1992).
Campbell, G.S. et al., “Evidence for Involvement of the Growth Hormone Receptor-associated Tyrosine Kinase in Actions of Growth Hormone,”J. Biol. Chem. 268(10):7427-7434, The American Society for Biochemistry and Molecular Biology, Inc. (Apr. 1993).
Carroll, M.P. et al., “Erythropoietin Induces Raf-1 Activation and Raf-1 is Required for Erythropoietin-mediated Proliferation,”J. Biol. Chem. 266(23):14964-14969, The American Society for Biochemistry and Molecular Biology, Inc. (1991).
Carroll, M.P. et al., “Interleukin-3 and Granulocyte-Macrophage Colony-stimulating Factor Mediate Rapid Phosphorylation and Activation of Cytosolic o-raf,”J. Biol. Chem. 265(32):19812-19817, The American Society for Biochemistry and Molecular Biology, Inc. (1990).
Cleveland, J.L. et al., “Tyrosine Kinase Oncogenes Abrogate Interleukin-3 Dependence of Murine Myeloid Cells through Signaling Pathways Involving c-myc: Conditional Regulation of c-myca Transcription by Temperature-Sensitive, v-abl,”Mol. Cell. Biol. 9(12):5685-5695, American Society (1989).
Duaanter-Fourt, I. et al., “Erythropoietin Induces the Tyrosine Phosphorylation of Its Own Receptor in Human Erythropoietin-responsive Cells,”J. Biol. Chem. 267(15):10670-10675, The American Society for Biochemistry and Molecular Biology, Inc. (May 1992).
Edgington, S.M., “Molecular Crosstalk: Will virology and growth-factor research aid cytokine drug discovery”Bio/Technol. 11:465-468, Nature Publishing Co. (Apr. 1993).
Firmbach-Kraft, I. et al., “tyk2, Prototype of a novel class of non-receptor tyrosine kinase genes,”Oncogene 5:1329-1336, Macmillan Press Ltd. (1990).
Fu, X.-Y., “A Transcription Factor with SH2 and SH3 Domains is Directly Activated by an Interferon α-induced Cytoplasmic Protein Tyrosine Kinase(s),”Cell 70:323-335, Cell Press (Jul. 1992).
Fu, X.-Y. et al., “The proteins of ISGF-3, the interferon α-induced transcriptional activator, define a gene family involved in signal transduction,”Proc. Natl. Acad. Sci. USA 89:7840-7843, National Academy of Sciences of the USA (Aug. 1992).
Fung, M.R. et al., “A Tyrosine Kinase Physically Associates With the β-Subunit of the Human IL-2 Receptor,”J. Immunol. 147(4):1253-1260, The American Association of Immunologists (1991).
Gilmour, K.C. and N. C. Reich, “Receptor to nucleus signaling by prolactin and interleukin 2 via activation of latent DNA-binding factors,”Proc. Natl. Acad. Sci. USA 91:6850-6854, National Academy of Science of the USA (Jul. 1994).
Goodman, P.A. et al., “Role of Tyrosine Kinases in Induction of the c-jun Proto-oncogene in Irradiated B-lineage Lymphoid Cells,”J. Biol. Chem. 273:17742-17748, The American Society for Biochemistry and Molecular Biology, Inc. (Jul. 1998).
Hanks, S.K. et al., “The Protein Kinase Family: Conserved Features and Deduced Phylogeny of the Catalytic Domains,”Science 241:42-52, Association for the Advancement of Science (1988).
Harpur, A.S. et al., “JAK2, a third member of the JAK family of protein tyrosine kinases,”Oncogene 7:1347-1353, Macmillan Press Ltd. (Jul. 1992).
Howard, O.M.Z. et al., “Characterization of a class 3 tyrosine kinase,”Oncogene 7:895-900, Macmillan Press Ltd. (May 1992).
Hunter, T., “A Thousand and One Protein Kinases,”Cell 50:823-829, Cell Press (1987).
Hunter, T., “Cytokine Connections,”Nature 366:114-116, Macmillan Publishers Ltd. (Nov. 1993).
Ihle, J.N., “Interleukin-3 and Hematopoiesis,” in:Interleukins: Molecular Biology and Immunology, Kishimoto, T., ed., Karger, Basel, pp. 65-106 (1992).
Ihle, J.N. and D. Askew, “Origins and Properties of Hematopoietic Growth Factor-Dependent Cell Lines,”Int. J. Cell Cloning 7(2):68-91 AlphaMed Press (1989).
Ihle, J.N., “Cytokine receptor signalling,”Nature 377:591-594, Macmillan Publishers Ltd. (Oct. 1995).
Ip, N.Y. et al., “CNTF and LIF Act on Neuronal Cells via Shared Signaling Pathways That Involve the IL-6 Signal Transducing Receptor Component sp130,”Cell 69:1121-1132, MIT Press (Jun. 1992).
Igfort, R.J. et al., “Interleukin 3 binds to a 140-kDa phosphotyrosine-containing cell surface protein,”Proc. Natl. Acad. Sci. USA 85:7982-7986, National Academy of Sciences of the USA (1988).
Kappel, C.A. et al., “Regulating gene expression in transgenic animals,”Curr. Opin. Biotech. 3:548-553, Current Biology Ltd. (Oct. 1992).
Koch, C.A. et al., “SH2 and SH3 Domains: Elements That Control Interactions of Cytoplasmic Signaling Proteins,”Science 252:668-674, Association for the Advancement of Science (1991).
Linnekin, D. et al., “Association of the erythropoietin receptor with protein tyrosine kinase activity,”Proc. Natl. Acad. Sci. USA 89:6237-6241, National Academy of Sciences of the USA (Jul. 1992).
Linnekin, D. and W.L. Farrar, “Signal transduction of human interleukin 3 and granulocyte-macrophage colony-stimulating factor through serine and tyrosine phosphorylation,”Biochem. J. 271:317-324, London Portland Press on Behalf Of The Biochemical Society (1990).
Maliazewski, C.R. and W.C. Fanslow, “Soluble receptors for

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Jak kinases and regulation of cytokine signal transduction does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Jak kinases and regulation of cytokine signal transduction, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Jak kinases and regulation of cytokine signal transduction will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3515954

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.