Immuno-stimulating polysaccharide substance from Phellinus...

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Fungi

Reexamination Certificate

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C435S911000, C435S072000, C435S171000, C424S093500

Reexamination Certificate



There is disclosed novelPhellinus linteus Yoo.This mushroom is identified as novel as analyzed by restriction fragment length polymorphism and by microbiological features. A polysaccharide substance isolated from the fruiting bodies or mycelia the strain and otherPhellinusspp. has an anticancer activity by inciting the cytotoxicity of T-cells and the antibody forming potency of B-cells. Also, the polysaccharide substance shows a potent activity against cancer metastasis. The polysaccharide substance, which can stimulate the immunity of the body, may be effective in the prophylaxis and treatment of immune-related diseases, such as cancers and AIDS, and in the study on the basic mechanism of the diseases.

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patent: 10-088188 (1999-09-01), None
patent: 97-15743 (1997-04-01), None
Lee et al. The Korean Jouranl of Mycology. Dec. 1995. vol. 23. No. 4, pp. 325-331.
Han et al., Immunopharmacology 1999;41:157-164.
Song et al., Chem. Pharm. Bull. 1995;43(12):2105-2108.


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