Factor VIII:C nucleic acid molecules

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S093100, C424S200100, C514S04400A, C536S024500, C536S023400

Reexamination Certificate

active

07138505

ABSTRACT:
Methods and compositions are provided for recombinant DNA production of Factor VIIIC and truncated derivatives thereof. Based on amino acid sequences, probes are developed for isolating messenger RNA, cDNA and/or chromosomal DNA encoding for Factor VIIIC. The Factor VIIIC gene in its entirety, a fragment thereof, or a cDNA is then used for expression of Factor VIIIC in a host.The bacteriophage λFVIII23D containing the 14.43 kb EcoRI fragment was deposited at the A.T.C.C. on Jan. 4, 1984 and given Accession No. 40094. Also, the vector pSVF8-200 was deposited at the A.T.C.C. on Jul. 17, 1985 and given Accession No. 40190.

REFERENCES:
patent: 4237224 (1980-12-01), Cohen et al.
patent: 4361509 (1982-11-01), Zimmerman et al.
patent: 4363877 (1982-12-01), Goodman et al.
patent: 4394443 (1983-07-01), Weissman et al.
patent: 4419446 (1983-12-01), Howley et al.
patent: 4649132 (1987-03-01), Zimmerman et al.
patent: 4657894 (1987-04-01), Zimmerman et al.
patent: 4716117 (1987-12-01), Kuo et al.
patent: 4749780 (1988-06-01), Andersson et al.
patent: 4757006 (1988-07-01), Toole et al.
patent: 5618788 (1997-04-01), Capon et al.
patent: 53519 (1984-03-01), None
patent: 083483 (1983-07-01), None
patent: 0120694 (1984-03-01), None
patent: 0123945 (1984-11-01), None
patent: 8404541 (1984-11-01), None
patent: 0150735 (1985-01-01), None
patent: 0143081 (1985-05-01), None
patent: 0182448 (1985-05-01), None
patent: 0157556 (1985-10-01), None
patent: 0160457 (1985-11-01), None
patent: 0182372 (1986-05-01), None
patent: 0232112 (1987-01-01), None
patent: 0197901 (1987-10-01), None
patent: WO 83/04029 (1983-11-01), None
patent: 8400594 (1985-02-01), None
patent: 8600774 (1986-10-01), None
Fulcher et al.,Blood(1983) 61:807.
Fulcher et al.,J. Clinical Invest.(1985) 76:117-124.
Orr et al.,Mol. Genetics of Clotting Factors, p. 54 in Thrombosis and Haemostasis, vol. 59, No. 1.
Rotblat et al.,Biochemistry(1985) 24:4294-4300.
Toole et al.,Nature(1984) 312:342-347.
Truett et al.,DNA(1985) 4:333-349.
Vehar et al.,Nature(1984) 312:337-342.
Wood et al.,Nature(1984) 321:330-337.
Katz et al.,J. Immunol.(1980) 124(2):819-824.
Andersson et al.,Proc. natl. Acad. Sci.(1986) 83:2979-2983.
Austen,British J. Hematology(1979) 43:669-674.
Gitschier et al.,Nature(1985) 312:326-330.
Bloom et al.,Nature(1983) 303:474-475.
Burke et al.,J. Biol. Chem.(1986) 261: 12574-12578.
Chan et al.,Chem. Abstracts(1984) 100:214.
Choo et al.,Nature(1983) 299:178-180.
Eaton et al.,Biochem.(1986) 25(26):8343-8347.
Eaton et al.,Biochem.(1986) 25:505-512.
Fass et al.,Blood(1982) 59:594-600.
Fass et al.,Proc. Natl. Acad. Sci.(1985) 82:1688:1691.
Fay et al.,Proc. Natl. Acad. Sci.(1982) 79:7200-7204.
Fulcher et al.,Blood(1984) 63(2):486-489.
Fulcher et al.,Chem. Abstr.(1983) 98(21):450.
Orr et al.,J. Inter. Soc. Throm. Hemo.(1985) 54(1):S321.
Peake et al.,Clin. Sci.(1984) 67:561-567.
Rotblat et al.,Biological Abstracts(1984) 77:4443.
Rotblat.,J. Lab. and Clin. Med.(1983) 101:736-746.
Toole et al.,Proc. Natl. Acad. Sci.(1986) 83:5939-5942.
Tuddenham et al.,J. Clin. Lab. Med.(1979) 93:40-53.
Weinstein et al.,Proc. Natl. Acad. Sci.(1981) 78:5137-5141.
Amended claim set filed in European patent application No. 91113267.8 (letter to European Patent Office dated Nov. 8, 1999).
Antakly et al., •2u-Globulin is present in the rat anterior pituitary,Proc. Natl. Acad. Sci. U.S.A. 80, 4000-02, Jul. 1983.
Benton & Davis, Screening •gt Recombinant Clones by Hybridization to Single Plaques in situ,Science 196, 180-82, Feb. 7, 1997.
Chirgwin et al., Isolation of Biologically Active Ribonucleic Acid from Sources Enriched in Ribonuclease,Biochemistry 18, 5294-99, 1979.
Choo et al., Molecular cloning of the gene for human anti-haemophilic factor IX,Nature 299, 178-80, Sep. 9, 1982.
Craig & Hall, Recombinant DNA technology: application to the characterization and expression of polypeptide hormones, in Williamson, ed.,Genetic Engineering 4, 58-125, 1983.
Grunstein & Hogness, Colony hybridization: A method for the isolation of cloned DNAs that contain a specific gene,Proc. Natl. Acad. Sci. U.S.A. 72, 3961-65, Oct. 1975.
Holmes & Quigley, A Rapid Boiling Method for the Preparation of Bacterial Plasmids,Anal. Biochem. 114, 193-97, 1981.
Main and auxiliary requests filed in Eurpoean patent application No. 91113267.8 (letter to European Patent Office dated Sep. 21, 2000).
Maniatis et al., Molecular Cloning: A Laboratory Manual, Cold Spring Harbor Laboratory, 1982, Table of Contents.
Maxam & Gilbert, A new method for sequencing DNA,Proc. Natl. Acad. Sci. U.S.A. 74, 560-64, Feb. 1977.
Messing et al., Filamentous coliphage M13 as a cloning vehicle: Insertion of a HindII fragment of thelacregulatory region in M13 replicative formin vitro, Proc. Natl. Acad. Sci. U.S.A. 74, 3642-46, 1977.
Mesterovic et al., Detection of rennin mRNA in mouse kidney and submandibular gland by hybridization with rennin cDNA,Endocrinology 113, 1179-81, 1983.
Okayama & Berg, A cDNA Cloning Vector That Permits Expression of cDNA Inserts in Mammalian Cells,Mol. Cell. Biol. 3, 280-89, Feb. 1983.
Rigby et al., Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase,J. Mol. Biol. 113, 237-51, 1977.
Southern, Detection of Specific Sequences Among DNA Fragments Separated by Gel Electrophoresis,J. Mol. Biol. 98, 503-17, 1975.
Toole et al., Molecular cloning of a cDNA encoding human antihaemophilic factor,Nature 312, 342-47, Nov. 22, 1984.
Truett et al., Characterization of the Polypeptide Composition of Human Factor VIII:C and the Nucleotide Sequence and Expression of the Human Kidney cDNA,DNA 4, 333-49, 1985.
Unterman et al., Cloning and sequence of several •2u-globulin cDNAs,Proc. Natl. Acad. Sci. U.S.A. 78, 3478-82, 1981.
Weinstock et al., Open reading frame expression vectors: A general method for antigen production inEscherichia coliusing protein fusion to β-galactosidase,Proc. Natl. Acad. Sci. U.S.A. 80, 4432-36, Jul. 1983.
Yansura et al., Biosynthetic vaccine for foot-and-mouth disease, Advances in Genetic Technology: Molecular Genetics of Plants and Animals, pp. 479-93, 1983.
Marcelletti et al.,J. Immunol.(1984) 133(6):2845-2851.
Marcelletti et al.,J. Immunol.(1984) 133(6):2837-2844.
Zuraw et al.,J. Immunol.(1981) 127(3):1169-1177.
Bloom et al.,Nature(1983) 303:474-475.
Burke et al.,J. Biol. Chem.(1986) 261: 12574-12578.
Chan et al.,Chem. Abstracts(1984) 100:214.
Choo et al.,Nature(1983) 299:178-180.
Eaton et al.,Biochem.(1986) 25(26):8343-8347.
Eaton et al.,Biochem.(1986) 25:505-512.
Fass et al.,Blood(1982) 59:594-600.
Fass et al.,Proc. Natl. Acad. Sci.(1985) 82:1688:1691.
Fay et al.,Proc. Natl. Acad. Sci.(1982) 79:7200-7204.
Fulcher et al.,Blood(1984) 63(2):486-489.
Fulcher et al.,Chem. Abstr.(1983) 98(21):450.
Fulcher et al.,Proc. Natl. Acad. Sci.(1982) 79:1648-1652.
Gitschier et al.,Nature(1985) 315:427-430.
Hybritech Data Sheet (Catalogue #1432).
Jaye et al.,Nuc. Acids Res.(1983) 11:2325-2335.
Kaufman et al.,Mol. and Cell. Bio.(1982) 2:1304-1319.
Kuo et al.,Abstr. For XI Int. Congress of Throm. Haemostasis(Jul. 1983) abstract No. 0818.
Kurachi et al.,Proc. Natl. Acad. Sci.(1982) 79:6461-6464.
Lawn et al.,Scientific American(Mar. 1986) pp. 48-54.
Lollar et al.,Biochemistry(1985) 24:8056-8064.
Maddox,Nature(1983) 306:528.
Muller et al.,Blood(1981) 58:1000-1006.
Muller et al.,Chem. Abstr.(1982) 96(5):480.
Nordfang et al.,Thrombosis and Haemostasis(1985) 54:586-590.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Factor VIII:C nucleic acid molecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Factor VIII:C nucleic acid molecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Factor VIII:C nucleic acid molecules will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3643029

All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.