Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
A polynucleotide sequence is provided, comprising: a nucleic acid sequence having at least 75% identity to SEQ ID NO: 1, wherein said nucleic acid sequence encodes recombinantBacillus anthracisProtective Antigen (rPA); or a fragment of said nucleic acid sequence wherein said fragment encodes a fragment of recombinantBacillus anthracisProtective Antigen (rPA).Also provided are expression vectors and host cells comprising the polynucleotide sequence of the invention, and methods for producing rPA or a fragment thereof.The invention further provides antigenic compositions and corresponding methods and uses for inducing an immune response.
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Lapcevich Randall K.
Solow Barbara T.
Dynport Vaccine Company LLC
Foley & Hoag LLP
Health Protection Agency
Zeman Robert A.
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