Antineoplastic agent-entrapping liposomes

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes


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4284022, A61K 3722, A61J 500, B01J 1302, B32B 516




Some of antineoplastic agents, for instance, adriamycin and daunorubicin, have a positive charge at physiological pH. Such drugs possess high affinity for binding to steroidal sulfate by means of electrostatic force. The invention utilizes this property to prepare steroidal sulfate liposomes having a net negative charge and encapsulating the antineoplastic agent.

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