Anti-sickling agents

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...


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2601125R, A61K 3702, C07C10352




The use of an anti-sickling agent of one or more of L-lysine-L-phenylalanine, L-lysine-L-tyrosine, L-histidine-L-lysine-L-tyrosine-L-histidine, in particular L-lysine-L-phenylalanine, and salts thereof is disclosed.
An anti-sickling composition which comprises one or more of L-lysine-L-phenylalanine, L-lysine-L-tyrosine, L-histidine-L-lysine-L-tyrosine-L-histidine and salts thereof in association with one or more sterile, pharmaceutically-acceptable carriers, diluents and adjuvants is also disclosed.

patent: 4261980 (1981-04-01), Cort
George R. Pettit, Synthetic Peptides, Elsevier Scientific Publishing Company, NY., 1980, V, p. 157.


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