A84575 antibiotics

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor


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435 713, 435822, C12R 101, C12N 120, C12P 2104




Newly discovered lipoglycopeptide antibiotic A84575 complex, comprising factors A, B, C, D, E, F, G, and H, is produced by submerged aerobic fermentation of a culture selected from Streptosporangeum carneum NRRL 18437, Streptosporangeum carneum NRRL 18505 or an A84575-producing mutant thereof. The antibiotics are active against Gram-positive bacteria.

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Waltho et al., "Structure Elucidation of the Glycopeptide Antibiotic Complex A40926," J. Chem. Soc. Perkin Trans I, 2103-2107 (1987).
S. B. Christenson et al., "Parvodicin, A Novel Glycopeptide from a New Species Actinomadura parvosata: Discovery, Taxonomy, Activity and Structure Elucidation," J. Antibiotics 60(7), 970-990 (1987).
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SmithKline Beckman Corp., "New Macrocyclic Glycopeptide Antibiotic Complex AAJ-271-Useful Therapeutically and as Animal Feed Additive, and New Actinomadura Parvosata Species," Derwent Abstract 88-030461/05 of EP-255-256-A.


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