9,11-Dihalo-PG.sub.2 compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters


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260239PF, 2603264, 260556R, 260556AR, 260408, 260557R, 260557D, 260559B, 260559R, 429365, 429317, 544391, 5445516, 562444, 562465, 546226, 546314, 560557, 568838, 568807, 568645, 568669, 542429, 542408, 560503, C07C17700




The present invention relates to certain 9,11-dideoxy-PGF-type compounds wherein the C-9 and C-11 carbon atoms are substituted by halogen. In particular, 9,11-chloro-, 9,11-bromo-, and 9,11-iodo-9,11-dideoxy-PGF compounds are disclosed.
These compounds are particularly useful for numerous pharmacological purposes, based on their ability to stimulate mammalian smooth muscle tissue.

patent: 3997587 (1976-12-01), Muchowski et al.


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