1'-am ino-2[(benzothiazolyl)methyl]spiro-[isoquinoline-4(1H),3'-

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...


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540543, A61K 31435, C07D47110




This invention relates to 1'-amino-2-[(benzothiazolyl)methyl]spiro[isoquinoline-4(1H),3'-pyrrolidine ]-1,2',3,5'(2H)-tetrones represented by formula (I): ##STR1## wherein: R.sup.1, R.sup.2 and R.sup.3 are independently hydrogen, alkyl containing 1 to 6 carbon atoms, halogen, lower alkoxy containing 1 to 6 carbon atoms, trifluoromethyl or nitro;

patent: 5037831 (1991-08-01), Malamas
patent: 5045544 (1991-03-01), Malamas
patent: 5102886 (1992-04-01), Malamas


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